6MYE
Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein scribble homolog | polymer | 95 | 9897.1 | 1 | UniProt (Q14160) Pfam (PF00595) | Homo sapiens (Human) | hScrib,Protein LAP4 |
| 2 | B (B) | Rho guanine nucleotide exchange factor 26, peptide | polymer | 13 | 1239.5 | 1 | UniProt (Q96DR7) | Homo sapiens | SH3 domain-containing guanine exchange factor |
| 3 | C (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 725 - 815 (UniProt: Q14160)
B: 42 - 52 (UniProt: Q96DR7)
| PDB | External Database | Details |
|---|---|---|
| Gly 721 | - | expression tag |
| Ala 722 | - | expression tag |
| Met 723 | - | expression tag |
| Gly 724 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 41 | - | expression tag |
| Lys 42 | Ser 42 | conflict |
| Nh2 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 11136.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 46.0 | |
| All* | Total formula weight | 11182.6 |
