6MV8
LDHA structure in complex with inhibitor 14
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | L-lactate dehydrogenase A chain | polymer | 332 | 36734.7 | 4 | UniProt (P00338) Pfam (PF00056) Pfam (PF02866) In PDB | Homo sapiens (Human) | LDH-A,Cell proliferation-inducing gene 19 protein,LDH muscle subunit,LDH-M,Renal carcinoma antigen NY-REN-59 |
| 2 | A, B, C, D | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 4 | Chemie (NAI) | |||
| 3 | A, B, C | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 3 | Chemie (EPE) | |||
| 4 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | A, C, D | (6S)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(2-hydroxyphenyl)-6-phenyl-5,6-dihydro-2H-pyran-2-one | non-polymer | 424.9 | 3 | Chemie (D3S) | |||
| 6 | B | LACTIC ACID | non-polymer | 90.1 | 1 | Chemie (LAC) | |||
| 7 | water | water | 18.0 | 721 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 146938.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 5125.7 | |
| All* | Total formula weight | 152064.4 |
