6MV5
Anti-PCSK9 fab 6E2 bound to the N-terminal peptide from PCSK9 (E32K)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Anti-PCSK9 fab 6E2 heavy chain | polymer | 224 | 24255.2 | 1 | Mus musculus (Mouse) | ||
| 2 | B (L) | Anti-PCSK9 fab 6E2 light chain | polymer | 219 | 24040.9 | 1 | UniProt (A0A097PUG4) Pfam (PF07686) Pfam (PF07654) | Mus musculus (Mouse) | |
| 3 | C (P) | Proprotein convertase subtilisin/kexin type 9 | polymer | 23 | 2494.6 | 1 | UniProt (Q8NBP7) | Homo sapiens | Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9 |
| 4 | D, G, H, I (H, L) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | E (H) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F, J (H, L) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | K, L, M (H, L, P) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
L: 1 - 106 (PDB: 6MV5)
L: 107 - 214 (UniProt: A0A097PUG4)
P: 32 - 53 (UniProt: Q8NBP7)
L: 107 - 214 (UniProt: A0A097PUG4)
P: 32 - 53 (UniProt: Q8NBP7)
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| Lys 32 | Glu 32 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50790.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 489.2 | |
| All* | Total formula weight | 51279.9 |
