6MUP
CENP-A nucleosome bound by two copies of CENP-C(CD) and two copies CENP-N(NT)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3-like centromeric protein A | polymer | 102 | 11993.0 | 2 | UniProt (P49450) Pfam (PF00125) | Homo sapiens (Human) | Centromere autoantigen A,Centromere protein A,CENP-A |
| 2 | B, F (B, F) | Histone H4 | polymer | 94 | 10604.5 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (Human) | |
| 3 | C, G (C, G) | Histone H2A type 1-C | polymer | 105 | 11494.4 | 2 | UniProt (Q93077) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (Human) | Histone H2A/l |
| 4 | D, H (D, H) | Histone H2B type 2-F | polymer | 92 | 10249.7 | 2 | UniProt (Q5QNW6) Pfam (PF00125) | Homo sapiens (Human) | |
| 5 | I (I) | DNA (147-MER) | polymer | 147 | 45141.9 | 1 | Homo sapiens | ||
| 6 | J (J) | DNA (147-MER) | polymer | 147 | 45582.2 | 1 | Homo sapiens | ||
| 7 | K, L (K, L) | Centromere protein C | polymer | 20 | 2508.8 | 2 | UniProt (Q03188) | Homo sapiens | CENP-C,Centromere autoantigen C,Centromere protein C 1,CENP-C 1,Interphase centromere complex protein 7 |
| 8 | M, N (M, N) | Centromere protein N | polymer | 212 | 25052.9 | 2 | UniProt (Q96H22) Pfam (PF05238) | Homo sapiens (Human) | CENP-N,Interphase centromere complex protein 32 |
Sequence modifications
C, G: 13 - 117 (UniProt: Q93077)
M, N: 1 - 212 (UniProt: Q96H22)
| PDB | External Database | Details |
|---|---|---|
| Ser 113 | Ala 114 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asp 84 | Glu 84 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 234530.9 | |
| All* | Total formula weight | 234530.9 |
