6MTH
E. coli DHFR complex modeled with three ligand states
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 165 | 18848.2 | 1 | UniProt (P0ABQ4) Pfam (PF00186) | Escherichia coli (strain K12) | |
| 2 | B, C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 3 | E, F, G, H (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | I, J (A) | (6S)-5,6,7,8-TETRAHYDROFOLATE | non-polymer | 445.4 | 2 | Chemie (THG) | |||
| 5 | K (A) | DIHYDROFOLIC ACID | non-polymer | 443.4 | 1 | Chemie (DHF) | |||
| 6 | L (A) | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ4)
| PDB | External Database | Details |
|---|---|---|
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| His 165 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18848.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1537.8 | |
| All* | Total formula weight | 20386.1 |
