6MSM
Phosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cystic fibrosis transmembrane conductance regulator | polymer | 1489 | 169352.6 | 1 | UniProt (P13569) Pfam (PF00664) Pfam (PF00005) Pfam (PF14396) In PDB | Homo sapiens (Human) | CFTR,ATP-binding cassette sub-family C member 7,Channel conductance-controlling ATPase,cAMP-dependent chloride channel |
2 | B | Piece of Molecule-1 | polymer | 17 | 1464.8 | 1 | Homo sapiens (Human) | ||
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
5 | A | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 5 | Chemie (POV) | |||
6 | A | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
A: 1 - 1480 (UniProt: P13569)
PDB | External Database | Details |
---|---|---|
Gln 1371 | Glu 1371 | engineered mutation |
Ser 1481 | - | expression tag |
Asn 1482 | - | expression tag |
Ser 1483 | - | expression tag |
Leu 1484 | - | expression tag |
Glu 1485 | - | expression tag |
Val 1486 | - | expression tag |
Leu 1487 | - | expression tag |
Phe 1488 | - | expression tag |
Gln 1489 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 170817.4 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 5250.0 | |
All* | Total formula weight | 176067.4 |