6MRP

Structure of the Bovine p85a BH domain R228E mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Phosphatidylinositol 3-kinase regulatory subunit alpha	polymer	220	24476.0	2	UniProt (P23727) Pfam (PF00620) In PDB	Bos taurus (Bovine)	PtdIns-3-kinase regulatory subunit alpha,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha
2		water	water		18.0	106	Chemie (HOH)

Sequence modifications

B, A: 110 - 319 (UniProt: P23727)

PDB	External Database	Details
Gly 100	-	expression tag
Pro 101	-	expression tag
Leu 102	-	expression tag
Gly 103	-	expression tag
Ser 104	-	expression tag
Thr 105	-	expression tag
Glu 106	-	expression tag
Ala 107	-	expression tag
Asp 108	-	expression tag
Ser 109	-	expression tag
Glu 228	Arg 228	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48952.0
All*	Total formula weight	48952.0

*Water molecules are not included.