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6MQG

Crystal structure of KRAS V14I-GDP demonstrating open switch 1 conformation - Form 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTPase KRaspolymer16719069.51UniProt (P01116)
Pfam (PF00071)
Homo sapiens (Human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3C
(A)
waterwater18.0193Chemie (HOH)
Sequence modifications
A: 3 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Ile 14Val 14engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19069.5
Non-Polymers*Number of molecules1
Total formula weight443.2
All*Total formula weight19512.7
*Water molecules are not included.

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PDB entries from 2025-07-16

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