6MQG
Crystal structure of KRAS V14I-GDP demonstrating open switch 1 conformation - Form 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTPase KRas | polymer | 167 | 19069.5 | 1 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 3 | C (A) | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A: 3 - 169 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Ile 14 | Val 14 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19069.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 443.2 | |
| All* | Total formula weight | 19512.7 |
