6MOI
Dimeric DARPin C_angle_R5 complex with EpoR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dimeric DARPing CCR5 (C_angle_R5) | polymer | 231 | 24343.8 | 1 | synthetic construct | ||
2 | B | Erythropoietin receptor | polymer | 229 | 25129.4 | 1 | UniProt (P19235) Pfam (PF09067) Pfam (PF00041) In PDB | Homo sapiens (Human) | EPO-R |
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
7 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
8 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
9 | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
B: 8 - 225 (UniProt: P19235)
PDB | External Database | Details |
---|---|---|
Phe 3 | - | expression tag |
Ala 4 | - | expression tag |
Gly 5 | - | expression tag |
Ser 6 | - | expression tag |
Ala 7 | - | expression tag |
Gln 52 | Asn 76 | conflict |
Gln 164 | Asn 188 | conflict |
Lys 226 | - | expression tag |
Glu 227 | - | expression tag |
Lys 228 | - | expression tag |
Ala 229 | - | expression tag |
Ala 230 | - | expression tag |
Ala 231 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 49473.2 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 1311.9 | |
All* | Total formula weight | 50785.2 |