6MNE
CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRONE AND NADP+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Estradiol 17-beta-dehydrogenase 1 | polymer | 328 | 34989.0 | 2 | UniProt (P14061) Pfam (PF00106) | Homo sapiens (Human) | 17-beta-hydroxysteroid dehydrogenase type 1,17-beta-HSD 1,20 alpha-hydroxysteroid dehydrogenase,20-alpha-HSD,E2DH,Placental 17-beta-hydroxysteroid dehydrogenase,Short chain dehydrogenase/reductase family 28C member 1 |
| 2 | C, F (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, G (A, B) | (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one | non-polymer | 270.4 | 2 | Chemie (J3Z) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69978.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2119.6 | |
| All* | Total formula weight | 72097.6 |
