6MKV
Crystal structure of Retinal-bound holo Q108K:K40L:T51W domain-swapped dimer of human cellular retinol binding protein 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Retinol-binding protein 2 | polymer | 133 | 15667.6 | 4 | UniProt (P50120) Pfam (PF00061) | Homo sapiens (Human) | Cellular retinol-binding protein II,CRBP-II |
| 2 | E, I, K (B, C, D) | RETINAL | non-polymer | 284.4 | 3 | Chemie (RET) | |||
| 3 | F, G, J, L, M... (B, C, D) | ACETATE ION | non-polymer | 59.0 | 7 | Chemie (ACT) | |||
| 4 | H, P (B, D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 133 (UniProt: P50120)
| PDB | External Database | Details |
|---|---|---|
| Leu 40 | Lys 41 | engineered mutation |
| Trp 51 | Thr 52 | engineered mutation |
| Lys 108 | Gln 109 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62670.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1450.8 | |
| All* | Total formula weight | 64121.2 |
