6MKO
Crystallographic solvent mapping analysis of glycerol bound to APE1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-(apurinic or apyrimidinic site) lyase | polymer | 285 | 32011.4 | 1 | UniProt (P27695) Pfam (PF03372) | Homo sapiens (Human) | APEX nuclease, APEN, Apurinic-apyrimidinic endonuclease 1, APE-1, REF-1, Redox factor-1 |
| 2 | B, C (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | D (A) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 40 - 318 (UniProt: P27695)
| PDB | External Database | Details |
|---|---|---|
| Gly 34 | - | expression tag |
| Ser 35 | - | expression tag |
| His 36 | - | expression tag |
| Met 37 | - | expression tag |
| Ala 38 | - | expression tag |
| Ser 39 | - | expression tag |
| Ala 138 | Cys 138 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32011.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 32195.6 |
