6MEO
Structural basis of coreceptor recognition by HIV-1 envelope spike
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Envelope glycoprotein gp160 | polymer | 461 | 51465.0 | 1 | UniProt (Q70145) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 2 | B (A) | T-cell surface glycoprotein CD4 | polymer | 176 | 19541.2 | 1 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) | Homo sapiens (Human) | T-cell surface antigen T4/Leu-3 |
| 3 | C (B) | C-C chemokine receptor type 5 | polymer | 313 | 36343.0 | 1 | UniProt (P51681) Pfam (PF00001) | Homo sapiens (Human) | CCR5,CHEMR13,HIV-1 fusion coreceptor |
| 4 | D, G, H, I, K... (C, F, H, I, K...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, J (D, J) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 6 | F (E) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42227JK) | |||
| 7 | M, O, P, Q, R... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 8 | N (G) | beta-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (BMA) | |||
| 9 | U (B) | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (A2G) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 107349.2 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4630.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1949.8 | |
| All* | Total formula weight | 113929.4 |
