6MD4
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Rosiglitazone and Oleic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 275 | 31449.5 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | C (A) | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL) | non-polymer | 357.4 | 1 | Chemie (BRL) | |||
3 | D (A) | OLEIC ACID | non-polymer | 282.5 | 1 | Chemie (OLA) | |||
4 | E, F (A, B) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 62899.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 639.9 | |
All* | Total formula weight | 63538.9 |