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6MD4

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Rosiglitazone and Oleic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor gammapolymer27531449.52UniProt (P37231)
Pfam (PF00104)
Homo sapiens (Human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2C
(A)
2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL)non-polymer357.41Chemie (BRL)
3D
(A)
OLEIC ACIDnon-polymer282.51Chemie (OLA)
4E, F
(A, B)
waterwater18.0224Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62899.0
Non-Polymers*Number of molecules2
Total formula weight639.9
All*Total formula weight63538.9
*Water molecules are not included.

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PDB entries from 2024-10-30

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