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6MBL

SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, Second P212121 Crystal Form

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(Y)
Actin Peptidepolymer151788.01UniProt (P60709)Homo sapiensBeta-actin
2B
(A)
Histone-lysine N-methyltransferase setd3polymer59967753.51UniProt (Q86TU7)
Pfam (PF00856)
Pfam (PF09273)
Homo sapiens (Human)SET domain-containing protein 3
3C
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
4D, E, F, G, H...
(A)
1,2-ETHANEDIOLnon-polymer62.110Chemie (EDO)
5N, O
(Y, A)
waterwater18.0139Chemie (HOH)
Sequence modifications
A: 0 - 593 (UniProt: Q86TU7)
PDBExternal DatabaseDetails
Gly -5-expression tag
Pro -4-expression tag
Leu -3-expression tag
Gly -2-expression tag
Ser -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight69541.5
Non-Polymers*Number of molecules11
Total formula weight1005.1
All*Total formula weight70546.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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