6MBJ
SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, P21 Crystal Form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | Y, Z | Actin Peptide | polymer | 15 | 1788.0 | 2 | UniProt (P60709) In PDB | Homo sapiens | Beta-actin |
| 2 | A, B | Histone-lysine N-methyltransferase setd3 | polymer | 599 | 67753.5 | 2 | UniProt (Q86TU7) Pfam (PF00856) Pfam (PF09273) In PDB | Homo sapiens (Human) | SET domain-containing protein 3 |
| 3 | Y, B, A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 35 | Chemie (EDO) | |||
| 4 | B, A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 7 | water | water | 18.0 | 611 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 593 (UniProt: Q86TU7)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 139083.0 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 3335.6 | |
| All* | Total formula weight | 142418.6 |
