6MBD
Human Mcl-1 in complex with the designed peptide dM1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 155 | 17694.1 | 2 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | C, D (C, D) | dM1 | polymer | 25 | 2625.0 | 2 | synthetic construct | ||
| 3 | E, F, G, H, I... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A, B: 172 - 324 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly 170 | - | expression tag |
| Ser 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 40638.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 392.5 | |
| All* | Total formula weight | 41030.8 |
