6M97

Crystal structure of the high-affinity copper transporter Ctr1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Chimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562	polymer	234	26272.5	1	UniProt (C0HAK2) UniProt (P0ABE7) Pfam (PF04145) Pfam (PF07361)	Salmo salar (Atlantic salmon)	high affinity copper uptake protein 1 isoform X1,Cytochrome b-562,high affinity copper uptake protein 1 isoform X1
2	B, C (A)	HEXATANTALUM DODECABROMIDE	non-polymer		2044.5	2	Chemie (TBR)
3	D (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 41 - 93 (UniProt: C0HAK2)
A: 1001 - 1106 (UniProt: P0ABE7)

PDB	External Database	Details
Trp 1007	Met 29	engineered mutation
Ile 1102	His 124	engineered mutation
Leu 1106	Arg 128	engineered mutation

A: 121 - 186 (UniProt: C0HAK2)

PDB	External Database	Details
Ser 187	-	expression tag
Asn 188	-	expression tag
Ser 189	-	expression tag
Leu 190	-	expression tag
Glu 191	-	expression tag
Val 192	-	expression tag
Leu 193	-	expression tag
Phe 194	-	expression tag
Gln 195	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26272.5
Non-Polymers*	Number of molecules	3
	Total formula weight	4154.5
All*	Total formula weight	30427.0

*Water molecules are not included.