6M94

Monophosphorylated pSer33 b-Catenin peptide bound to b-TrCP/Skp1 Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	F-box/WD repeat-containing protein 1A	polymer	432	49418.4	1	UniProt (Q9Y297) Pfam (PF12937) Pfam (PF00400) In PDB	Homo sapiens (Human)	E3RSIkappaB,Epididymis tissue protein Li 2a,F-box and WD repeats protein beta-TrCP,pIkappaBalpha-E3 receptor subunit
2	B	S-phase kinase-associated protein 1	polymer	144	16459.7	1	UniProt (P63208) Pfam (PF01466) Pfam (PF03931) In PDB	Homo sapiens (Human)	Cyclin-A/CDK2-associated protein p19,p19A,Organ of Corti protein 2,OCP-2,Organ of Corti protein II,OCP-II,RNA polymerase II elongation factor-like protein,SIII,Transcription elongation factor B polypeptide 1-like,p19skp1
3	C	Catenin beta-1	polymer	33	3544.7	1	UniProt (P35222) In PDB	Homo sapiens	Beta-catenin
4	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	A	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS)

Sequence modifications

A: 139 - 569 (UniProt: Q9Y297)

PDB	External Database	Details
Ser 138	-	expression tag

B: 2 - 145 (UniProt: P63208)

PDB	External Database	Details
-	Asp 37	deletion
-	Asp 38	deletion
-	Glu 39	deletion
-	Gly 40	deletion
-	Asp 41	deletion
-	Asp 42	deletion
-	Pro 71	deletion
-	Pro 72	deletion
-	Glu 73	deletion
-	Asp 74	deletion
-	Asp 75	deletion
-	Glu 76	deletion
-	Asn 77	deletion
-	Lys 78	deletion
-	Glu 79	deletion
-	Lys 80	deletion
-	Arg 81	deletion
-	Thr 82	deletion

C: 17 - 48 (UniProt: P35222)

PDB	External Database	Details
Cys 16	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	69422.9
Non-Polymers*	Number of molecules	2
	Total formula weight	173.1
All*	Total formula weight	69596.0

*Water molecules are not included.