6M8D
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with diosmetin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Inositol polyphosphate multikinase,Inositol polyphosphate multikinase | polymer | 261 | 29827.9 | 1 | UniProt (Q8NFU5) Pfam (PF03770) In PDB | Homo sapiens (Human) | Inositol 1,3,4,6-tetrakisphosphate 5-kinase,Inositol 1,3,4,6-tetrakisphosphate 5-kinase |
2 | A | 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one | non-polymer | 300.3 | 1 | Chemie (J8D) | |||
3 | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A: 50 - 372 (UniProt: Q8NFU5)
A: 378 - 416 (UniProt: Q8NFU5)
PDB | External Database | Details |
---|---|---|
Gly 46 | - | expression tag |
Ser 47 | - | expression tag |
Phe 48 | - | expression tag |
Thr 49 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 373 | - | linker |
Gly 374 | - | linker |
Ser 375 | - | linker |
Gly 376 | - | linker |
Gly 377 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29827.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 300.3 | |
All* | Total formula weight | 30128.2 |