6M67

The Cryo-EM Structure of Human Pannexin 1 with D376E/D379E Mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Pannexin-1	polymer	440	49791.6	7	UniProt (Q96RD7) Pfam (PF00876) In PDB	Homo sapiens (Human)

Sequence modifications

A, B, C, D, E, F, G: 1 - 426 (UniProt: Q96RD7)

PDB	External Database	Details
Glu 376	Asp 376	engineered mutation
Glu 379	Asp 379	engineered mutation
Gly 427	-	expression tag
Ser 428	-	expression tag
Gly 429	-	expression tag
Ser 430	-	expression tag
His 431	-	expression tag
His 432	-	expression tag
His 433	-	expression tag
His 434	-	expression tag
His 435	-	expression tag
His 436	-	expression tag
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag
His 440	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	348541.4
All*	Total formula weight	348541.4

*Water molecules are not included.