6M5Y
Structure of human galectin-1 tandem-repeat mutant with lactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Galectin-1,Galectin-1 | polymer | 272 | 29382.7 | 1 | UniProt (P09382) Pfam (PF00337) | Homo sapiens (Human) | |
| 2 | B (B) | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
| 3 | C (C) | beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900008) GlyTouCan (G88362QR) | alpha-lactose | ||
| 4 | D (A) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A: 1 - 135 (UniProt: P09382)
A: 139 - 272 (UniProt: P09382)
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | Cys 3 | engineered mutation |
| Ser 17 | Cys 17 | engineered mutation |
| Ser 61 | Cys 61 | engineered mutation |
| Ser 89 | Cys 89 | engineered mutation |
| Ser 131 | Cys 131 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 136 | - | linker |
| Ser 137 | - | linker |
| Ser 138 | - | linker |
| Ser 140 | Cys 3 | engineered mutation |
| Ser 154 | Cys 17 | engineered mutation |
| Ser 198 | Cys 61 | engineered mutation |
| Ser 226 | Cys 89 | engineered mutation |
| Ser 268 | Cys 131 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29382.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 684.6 | |
| All* | Total formula weight | 30067.3 |
