6M3I
Crystal structure of HPF1/PARP1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone PARylation factor 1 | polymer | 346 | 39495.1 | 1 | UniProt (Q9NWY4) Pfam (PF10228) | Homo sapiens (Human) | |
| 2 | B (B) | Poly [ADP-ribose] polymerase 1 | polymer | 253 | 28057.1 | 1 | UniProt (P09874) Pfam (PF00644) | Homo sapiens (Human) | PARP-1,ADP-ribosyltransferase diphtheria toxin-like 1,ARTD1,DNA ADP-ribosyltransferase PARP1,NAD(+) ADP-ribosyltransferase 1,ADPRT 1,Poly[ADP-ribose] synthase 1,Protein poly-ADP-ribosyltransferase PARP1 |
| 3 | C (B) | BENZAMIDE | non-polymer | 121.1 | 1 | Chemie (UNU) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
B: 788 - 1014 (UniProt: P09874)
| PDB | External Database | Details |
|---|---|---|
| Gly 660 | - | expression tag |
| Thr 661 | - | expression tag |
| Lys 662 | - | expression tag |
| Ser 663 | - | expression tag |
| Lys 664 | - | expression tag |
| Leu 665 | - | expression tag |
| Pro 666 | - | expression tag |
| Lys 667 | - | expression tag |
| Pro 668 | - | expression tag |
| Val 669 | - | expression tag |
| Gln 670 | - | expression tag |
| Asp 671 | - | expression tag |
| Leu 672 | - | expression tag |
| Ile 673 | - | expression tag |
| Lys 674 | - | expression tag |
| Met 675 | - | expression tag |
| Ile 676 | - | expression tag |
| Phe 677 | - | expression tag |
| Gly 780 | - | expression tag |
| Ser 781 | - | expression tag |
| Gly 782 | - | expression tag |
| Ser 783 | - | expression tag |
| Gly 784 | - | expression tag |
| Ser 785 | - | expression tag |
| Gly 786 | - | expression tag |
| Gly 787 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67552.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 121.1 | |
| All* | Total formula weight | 67673.4 |
