6M1I
CryoEM structure of human PAC1 receptor in complex with PACAP38
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Pituitary adenylate cyclase-activating polypeptide type I receptor | polymer | 406 | 47315.6 | 1 | Pfam (PF02793) Pfam (PF00002) UniProt (by SIFTS) (P41586) | Homo sapiens | |
| 2 | B (B) | Pituitary adenylate cyclase-activating polypeptide | polymer | 38 | 4547.3 | 1 | UniProt (P18509) Pfam (PF00123) | Homo sapiens | PACAP |
| 3 | C (C) | Nanobody 35 | polymer | 134 | 14714.3 | 1 | Lama glama | ||
| 4 | D (D) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (Human) | G gamma-I |
| 5 | E (E) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 341 | 37474.0 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (Human) | Transducin beta chain 1 |
| 6 | F (F) | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | polymer | 394 | 45683.4 | 1 | Pfam (PF00503) UniProt (by SIFTS) (P63092) | Homo sapiens |
Sequence modifications
E: 1 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 157595.8 | |
| All* | Total formula weight | 157595.8 |
