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6M1C

Crystal structure of RsmD methyltransferase of M. tuberculosis in complex with sinefungin reveals key interactions

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Possible methyltransferase (Methylase)polymer18919914.61UniProt (I6XFS7)
Pfam (PF03602)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2B
(A)
SINEFUNGINnon-polymer381.41Chemie (SFG)
3C
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
4D
(A)
waterwater18.053Chemie (HOH)
Sequence modifications
A: 1 - 188 (UniProt: I6XFS7)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19914.6
Non-Polymers*Number of molecules2
Total formula weight440.4
All*Total formula weight20355.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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