6M12
Crystal Structure of Rnase L in complex with SU11652
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (a, b) | Ribonuclease L | polymer | 717 | 81327.8 | 2 | UniProt (A5H025) Pfam (PF12796) Pfam (PF00069) Pfam (PF06479) | Sus scrofa (Pig) | |
| 2 | C, G (a, b) | 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE | non-polymer | 414.9 | 2 | Chemie (J60) | |||
| 3 | D, F (a, b) | [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate | non-polymer | 1165.6 | 2 | Chemie (25L) | |||
| 4 | E (a) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) |
Sequence modifications
a, b: 21 - 732 (UniProt: A5H025)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Met 18 | - | expression tag |
| Asp 19 | - | expression tag |
| Pro 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 162655.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 3256.0 | |
| All* | Total formula weight | 165911.7 |
