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6LX7

X-ray structure of human PPARalpha ligand binding domain-stearic acid co-crystals obtained by delipidation and cross-seeding

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Peroxisome proliferator-activated receptor alphapolymer27330856.11UniProt (Q07869)
Pfam (PF00104)
Homo sapiens
2B
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
3C
(A)
STEARIC ACIDnon-polymer284.51Chemie (STE)
4D
(A)
waterwater18.0201Chemie (HOH)
Sequence modifications
A: 200 - 468 (UniProt: Q07869)
PDBExternal DatabaseDetails
Gly 196-expression tag
Ser 197-expression tag
His 198-expression tag
Met 199-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight30856.1
Non-Polymers*Number of molecules2
Total formula weight376.6
All*Total formula weight31232.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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