6LX5

X-ray structure of human PPARalpha ligand binding domain-ciprofibrate co-crystals obtained by delipidation and co-crystallization

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Peroxisome proliferator-activated receptor alpha	polymer	273	30856.1	2	UniProt (Q07869) Pfam (PF00104)	Homo sapiens
2	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3	D, E, F, G (A, B)	2-{4-[(1S)-2,2-dichlorocyclopropyl]phenoxy}-2-methylpropanoic acid	non-polymer		289.2	4	Chemie (C5F)
4	H, I (A, B)	water	water		18.0	263	Chemie (HOH)

Sequence modifications

A, B: 200 - 468 (UniProt: Q07869)

PDB	External Database	Details
Gly 196	-	expression tag
Ser 197	-	expression tag
His 198	-	expression tag
Met 199	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61712.1
Non-Polymers*	Number of molecules	5
	Total formula weight	1248.7
All*	Total formula weight	62960.8

*Water molecules are not included.