6LWQ
Crystal structure of human NEIL1(R242) bound to duplex DNA containing a C:T mismatch
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, D, G) | Endonuclease 8-like 1 | polymer | 295 | 33329.2 | 3 | UniProt (Q96FI4) Pfam (PF01149) Pfam (PF09292) | Homo sapiens (Human) | DNA glycosylase/AP lyase Neil1,DNA-(apurinic or apyrimidinic site) lyase Neil1,Endonuclease VIII-like 1,FPG1,Nei homolog 1,NEH1,Nei-like protein 1 |
| 2 | B, E, H (B, E, H) | DNA (5'-D(*CP*GP*TP*CP*CP*AP*TP*GP*TP*CP*TP*AP*C)-3') | polymer | 13 | 3902.5 | 3 | Escherichia coli | ||
| 3 | C, F, I (C, F, I) | DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3') | polymer | 13 | 4016.6 | 3 | Escherichia coli | ||
| 4 | J, K, L, M, N (A, B, C, D, E) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A, D, G: 1 - 295 (UniProt: Q96FI4)
| PDB | External Database | Details |
|---|---|---|
| Arg 242 | Lys 242 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 123745.2 | |
| All* | Total formula weight | 123745.2 |
