6LWF
Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing guanidinohydantoin (Gh)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | Endonuclease 8-like 1 | polymer | 295 | 33260.2 | 2 | UniProt (Q96FI4) Pfam (PF01149) Pfam (PF09292) In PDB | Homo sapiens (Human) | DNA glycosylase/AP lyase Neil1,DNA-(apurinic or apyrimidinic site) lyase Neil1,Endonuclease VIII-like 1,FPG1,Nei homolog 1,NEH1,Nei-like protein 1 |
| 2 | B, E | DNA (5'-D(*CP*GP*TP*CP*CP*AP*(DGH)P*GP*TP*CP*TP*AP*C)-3') | polymer | 13 | 3933.6 | 2 | Escherichia coli | ||
| 3 | C, F | DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3') | polymer | 13 | 4016.6 | 2 | Escherichia coli | ||
| 4 | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 295 (UniProt: Q96FI4)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | Pro 2 | engineered mutation |
| Gln 3 | Glu 3 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 82420.7 | |
| All* | Total formula weight | 82420.7 |
