6LTW

Crystal structure of Apo form of I122A/I330A variant of S-adenosylmethionine synthetase from Cryptosporidium hominis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	S-adenosylmethionine synthase	polymer	414	45871.2	2	UniProt (A0A0S4TKQ5) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) In PDB	Cryptosporidium hominis
2	A, B	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	A, B	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
4		water	water		18.0	580	Chemie (HOH)

Sequence modifications

A, B: 1 - 406 (UniProt: A0A0S4TKQ5)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ala 122	Ile 122	variant
Ala 330	Ile 330	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91742.3
Non-Polymers*	Number of molecules	8
	Total formula weight	477.1
All*	Total formula weight	92219.4

*Water molecules are not included.