6LTD

Crystal Structure of Nonribosomal peptide synthetases (NRPS), FmoA3 (S1046A)-alpha-methyl-L-serine-AMP bound form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Nonribosomal peptide synthetase	polymer	1153	125243.7	2	UniProt (A0A077JG85) Pfam (PF00668) Pfam (PF00501) Pfam (PF13193) Pfam (PF00550)	Streptomyces sp. Sp080513GE-23
2	C, E (A, B)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	2	Chemie (AMP)
3	D, F (A, B)	alpha-methyl-L-serine	non-polymer		119.1	2	Chemie (EW6)

Sequence modifications

A, B: 1 - 1127 (UniProt: A0A077JG85)

PDB	External Database	Details
Met -15	-	expression tag
Asn -14	-	expression tag
His -13	-	expression tag
Lys -12	-	expression tag
Val -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
His 0	-	expression tag
Ala 1046	Ser 1046	engineered mutation
Ser 1128	-	expression tag
Ala 1129	-	expression tag
Trp 1130	-	expression tag
Ser 1131	-	expression tag
His 1132	-	expression tag
Pro 1133	-	expression tag
Gln 1134	-	expression tag
Phe 1135	-	expression tag
Glu 1136	-	expression tag
Lys 1137	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	250487.4
Non-Polymers*	Number of molecules	4
	Total formula weight	932.7
All*	Total formula weight	251420.1

*Water molecules are not included.