6LTC
Crystal Structure of Nonribosomal peptide synthetases (NRPS), FmoA3 (S1046A)-alpha-methyl-L-serine-AMP bound form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nonribosomal peptide synthetase | polymer | 1153 | 125243.7 | 1 | UniProt (A0A077JG85) | Streptomyces sp. Sp080513GE-23 | |
| 2 | B (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (34768) PubChem (83862) PubChem (40467049) PubChem (40469468) PubChem (446048) PubChem (44348067) PubChem (45358029) PubChem (40459109) PubChem (515384) PubChem (46874558) PubChem (638042) PubChem (46875232) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (5316444) PubChem (5742864) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (12163610) PubChem (12358355) PubChem (92144436) PubChem (122197642) PubChem (12358354) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 3 | C (A) | alpha-methyl-L-serine | non-polymer | 119.1 | 1 | Chemie (EW6) PubChem (94309) PubChem (439656) PubChem (7000050) | |||
| 4 | D, E, F, G (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | H, I, J, K, L... (A) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) PubChem (312) | |||
| 6 | N (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 1127 (UniProt: A0A077JG85)
| PDB | External Database | Details |
|---|---|---|
| Met -15 | - | expression tag |
| Asn -14 | - | expression tag |
| His -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Val -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| Ile -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Arg -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 1046 | Ser 1046 | engineered mutation |
| Ser 1128 | - | expression tag |
| Ala 1129 | - | expression tag |
| Trp 1130 | - | expression tag |
| Ser 1131 | - | expression tag |
| His 1132 | - | expression tag |
| Pro 1133 | - | expression tag |
| Gln 1134 | - | expression tag |
| Phe 1135 | - | expression tag |
| Glu 1136 | - | expression tag |
| Lys 1137 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 125243.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1063.3 | |
| All* | Total formula weight | 126307.0 |
