6LTC
Crystal Structure of Nonribosomal peptide synthetases (NRPS), FmoA3 (S1046A)-alpha-methyl-L-serine-AMP bound form
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Nonribosomal peptide synthetase | polymer | 1153 | 125243.7 | 1 | UniProt (A0A077JG85) Pfam (PF00668) Pfam (PF00501) Pfam (PF13193) Pfam (PF00550) In PDB | Streptomyces sp. Sp080513GE-23 | |
2 | A | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
3 | A | alpha-methyl-L-serine | non-polymer | 119.1 | 1 | Chemie (EW6) | |||
4 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
6 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 1127 (UniProt: A0A077JG85)
PDB | External Database | Details |
---|---|---|
Met -15 | - | expression tag |
Asn -14 | - | expression tag |
His -13 | - | expression tag |
Lys -12 | - | expression tag |
Val -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
Ile -4 | - | expression tag |
Glu -3 | - | expression tag |
Gly -2 | - | expression tag |
Arg -1 | - | expression tag |
His 0 | - | expression tag |
Ala 1046 | Ser 1046 | engineered mutation |
Ser 1128 | - | expression tag |
Ala 1129 | - | expression tag |
Trp 1130 | - | expression tag |
Ser 1131 | - | expression tag |
His 1132 | - | expression tag |
Pro 1133 | - | expression tag |
Gln 1134 | - | expression tag |
Phe 1135 | - | expression tag |
Glu 1136 | - | expression tag |
Lys 1137 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 125243.7 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1063.3 | |
All* | Total formula weight | 126307.0 |