6LTB

Crystal Structure of Nonribosomal peptide synthetases (NRPS), FmoA3 (S1046A)-AMPPNP bound form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Nonribosomal peptide synthetase	polymer	1153	125243.7	1	UniProt (A0A077JG85) Pfam (PF00668) Pfam (PF00501) Pfam (PF13193) Pfam (PF00550)	Streptomyces sp. Sp080513GE-23
2	B (A)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
3	C (A)	water	water		18.0	13	Chemie (HOH)

Sequence modifications

A: 1 - 1127 (UniProt: A0A077JG85)

PDB	External Database	Details
Met -15	-	expression tag
Asn -14	-	expression tag
His -13	-	expression tag
Lys -12	-	expression tag
Val -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
His 0	-	expression tag
Ala 1046	Ser 1046	engineered mutation
Ser 1128	-	expression tag
Ala 1129	-	expression tag
Trp 1130	-	expression tag
Ser 1131	-	expression tag
His 1132	-	expression tag
Pro 1133	-	expression tag
Gln 1134	-	expression tag
Phe 1135	-	expression tag
Glu 1136	-	expression tag
Lys 1137	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	125243.7
Non-Polymers*	Number of molecules	1
	Total formula weight	506.2
All*	Total formula weight	125749.9

*Water molecules are not included.