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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6LSS

Cryo-EM structure of a pre-60S ribosomal subunit - state preA

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
11Nucleolar GTP-binding protein 2polymer73183796.11UniProt (Q13823)
Pfam (PF08153)
Pfam (PF01926)
In PDB		Homo sapiens (Human)Autoantigen NGP-1
2228S rRNApolymer50701641892.61Homo sapiens (Human)
34Nucleolar GTP-binding protein 1polymer63474107.81UniProt (Q9BZE4)
Pfam (PF17835)
Pfam (PF06858)
Pfam (PF08155)
In PDB		Homo sapiens (Human)Chronic renal failure gene protein,GTP-binding protein NGB
455S rRNApolymer12038691.91GenBank (23898)Homo sapiens (Human)
56Eukaryotic translation initiation factor 6polymer24526620.01UniProt (P56537)
Pfam (PF01912)
In PDB		Homo sapiens (Human)eIF-6,B(2)GCN homolog,B4 integrin interactor,CAB,p27(BBP)
67Probable ribosome biogenesis protein RLP24polymer16319666.31UniProt (Q9UHA3)
Pfam (PF01246)
In PDB		Homo sapiens (Human)Ribosomal L24 domain-containing protein 1,Ribosomal protein L24-like
7828S rRNApolymer15650157.71Homo sapiens (Human)
89Zinc finger protein 593polymer13415230.21UniProt (O00488)
Pfam (PF12171)
In PDB		Homo sapiens (Human)Zinc finger protein T86
9B60S ribosomal protein L3polymer40346211.11UniProt (P39023)
Pfam (PF00297)
In PDB		Homo sapiens (Human)HIV-1 TAR RNA-binding protein B,TARBP-B,Large ribosomal subunit protein uL3
10C60S ribosomal protein L29polymer15917804.31UniProt (P47914)
Pfam (PF01779)
In PDB		Homo sapiens (Human)Cell surface heparin-binding protein HIP,Large ribosomal subunit protein eL29
11D60S ribosomal protein L4polymer42747804.61UniProt (P36578)
Pfam (PF00573)
Pfam (PF14374)
In PDB		Homo sapiens (Human)60S ribosomal protein L1,Large ribosomal subunit protein uL4
12E60S ribosomal protein L30polymer11512805.11UniProt (P62888)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL30
13F60S ribosomal protein L34polymer11713326.11UniProt (P49207)
Pfam (PF01199)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL34
14G60S ribosomal protein L7apolymer26630061.81UniProt (P62424)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3
15H60S ribosomal protein L35polymer12314593.61UniProt (P42766)
Pfam (PF00831)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL29
16I60S ribosomal protein L9polymer19221899.51UniProt (P32969)
Pfam (PF00347)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL6
17K60S ribosomal protein L36polymer10512290.91UniProt (Q9Y3U8)
Pfam (PF01158)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL36
18L60S ribosomal protein L27apolymer14816604.51UniProt (P46776)
Pfam (PF00828)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL15
19M60S ribosomal protein L37polymer9711111.01UniProt (P61927)
Pfam (PF01907)
In PDB		Homo sapiens (Human)G1.16,Large ribosomal subunit protein eL37
20N60S ribosomal protein L11polymer17820288.51UniProt (P62913)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Homo sapiens (Human)CLL-associated antigen KW-12,Large ribosomal subunit protein uL5
21O60S ribosomal protein L38polymer708238.91UniProt (P63173)
Pfam (PF01781)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL38
22P60S ribosomal protein L39polymer516426.81UniProt (P62891)
Pfam (PF00832)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL39
23Q60S ribosomal protein L13polymer21124321.71UniProt (P26373)
Pfam (PF01294)
In PDB		Homo sapiens (Human)Breast basic conserved protein 1,Large ribosomal subunit protein eL13
24RTranslation machinery-associated protein 16polymer20323912.41UniProt (Q96EY4)
Pfam (PF11176)
In PDB		Homo sapiens (Human)
25S60S ribosomal protein L14polymer21523485.01UniProt (P50914)
Pfam (PF01929)
In PDB		Homo sapiens (Human)CAG-ISL 7,Large ribosomal subunit protein eL14
26U60S ribosomal protein L15polymer20424207.31UniProt (P61313)
Pfam (PF00827)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL15
27V60S ribosomal protein L13apolymer20323633.41UniProt (P40429)
Pfam (PF00572)
In PDB		Homo sapiens (Human)23 kDa highly basic protein,Large ribosomal subunit protein uL13
28W60S ribosomal protein L36apolymer10612477.01UniProt (P83881)
Pfam (PF00935)
In PDB		Homo sapiens (Human)60S ribosomal protein L44,Cell growth-inhibiting gene 15 protein,Cell migration-inducing gene 6 protein,Large ribosomal subunit protein eL42
29X60S ribosomal protein L37apolymer9210299.41UniProt (P61513)
Pfam (PF01780)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL43
30Y60S ribosomal protein L17polymer18421443.21UniProt (P18621)
Pfam (PF00237)
In PDB		Homo sapiens (Human)60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1
31Z60S ribosomal protein L18polymer18821687.71UniProt (Q07020)
Pfam (PF17135)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL18
32a60S ribosomal protein L19polymer19623535.31UniProt (P84098)
Pfam (PF01280)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL19
33b60S ribosomal protein L18apolymer17620808.51UniProt (Q02543)
Pfam (PF01775)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL20
34c60S ribosomal protein L21polymer16018610.01UniProt (P46778)
Pfam (PF01157)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL21
35d60S ribosomal protein L22polymer12814813.01UniProt (P35268)
Pfam (PF01776)
In PDB		Homo sapiens (Human)EBER-associated protein,EAP,Epstein-Barr virus small RNA-associated protein,Heparin-binding protein HBp15,Large ribosomal subunit protein eL22
36e60S ribosomal protein L23polymer14014892.51UniProt (P62829)
Pfam (PF00238)
In PDB		Homo sapiens (Human)60S ribosomal protein L17,Large ribosomal subunit protein uL14
37g60S ribosomal protein L23apolymer15617740.21UniProt (P62750)
Pfam (PF03939)
Pfam (PF00276)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL23
38h60S ribosomal protein L26polymer14517303.41UniProt (P61254)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL24
39i60S ribosomal protein L27polymer13615835.81UniProt (P61353)
Pfam (PF00467)
Pfam (PF01777)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL27
40j60S ribosomal protein L31polymer12514494.91UniProt (P62899)
Pfam (PF01198)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL31
41k60S ribosomal protein L32polymer13515898.91UniProt (P62910)
Pfam (PF01655)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL32
42l60S ribosomal protein L28polymer13715784.61UniProt (P46779)
Pfam (PF01778)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL28
43m60S ribosomal protein L8polymer25728088.91UniProt (P62917)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL2
44n60S ribosomal protein L35apolymer11012564.71UniProt (P18077)
Pfam (PF01247)
In PDB		Homo sapiens (Human)Cell growth-inhibiting gene 33 protein,Large ribosomal subunit protein eL33
45o60S ribosomal protein L6polymer28832810.21UniProt (Q02878)
Pfam (PF03868)
Pfam (PF01159)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107
46p60S ribosomal protein L7polymer24829291.01UniProt (P18124)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL30
47r60S ribosomal protein L5polymer29734426.81UniProt (P46777)
Pfam (PF17144)
Pfam (PF14204)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL18
48zProtein LLP homologpolymer12915268.41UniProt (Q9BRT6)
Pfam (PF10169)
In PDB		Homo sapiens (Human)Protein LAPS18-like
492, 9, B, D, F...MAGNESIUM IONnon-polymer24.3250Chemie (MG)
50waterwater18.016Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains48
Total formula weight2757263.3
Non-Polymers*Number of molecules250
Total formula weight6076.3
All*Total formula weight2763339.6
*Water molecules are not included.

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PDB entries from 2024-07-10

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