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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6LSR

Cryo-EM structure of a pre-60S ribosomal subunit - state B

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
10Zinc finger protein 622polymer47754357.11UniProt (Q969S3)
Pfam (PF12171)
Pfam (PF12756)
In PDB		Homo sapiens (Human)Zinc finger-like protein 9
21Large subunit GTPase 1 homologpolymer65875336.41UniProt (Q9H089)
Pfam (PF01926)
In PDB		Homo sapiens (Human)hLsg1
3228S rRNApolymer50701641892.61Homo sapiens (Human)
4360S ribosomal export protein NMD3polymer53461396.91UniProt (Q96D46)
Pfam (PF04981)
Pfam (PF21193)
Pfam (PF21192)
In PDB		Homo sapiens (Human)hNMD3
555S rRNApolymer12038691.91GenBank (NR_023363)Homo sapiens (Human)
66Eukaryotic translation initiation factor 6polymer24526620.01UniProt (P56537)
Pfam (PF01912)
In PDB		Homo sapiens (Human)eIF-6,B(2)GCN homolog,B4 integrin interactor,CAB,p27(BBP)
785.8S rRNApolymer15650143.61GenBank (KY962518)Homo sapiens (Human)
8A60S ribosomal protein L10apolymer21724879.41UniProt (P62906)
Pfam (PF00687)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL1
9B60S ribosomal protein L3polymer40346211.11UniProt (P39023)
Pfam (PF00297)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL3
10C60S ribosomal protein L29polymer15917804.31UniProt (P47914)
Pfam (PF01779)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL29
11D60S ribosomal protein L4polymer42747804.61UniProt (P36578)
Pfam (PF00573)
Pfam (PF14374)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL4
12E60S ribosomal protein L30polymer11512805.11UniProt (P62888)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL30
13F60S ribosomal protein L34polymer11713326.11UniProt (P49207)
Pfam (PF01199)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL34
14G60S ribosomal protein L7apolymer26630061.81UniProt (P62424)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL8
15H60S ribosomal protein L35polymer12314593.61UniProt (P42766)
Pfam (PF00831)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL29
16I60S ribosomal protein L9polymer19221899.51UniProt (P32969)
Pfam (PF00347)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL6
17K60S ribosomal protein L36polymer10512290.91UniProt (Q9Y3U8)
Pfam (PF01158)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL36
18L60S ribosomal protein L27apolymer14816604.51UniProt (P46776)
Pfam (PF00828)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL15
19M60S ribosomal protein L37polymer9711111.01UniProt (P61927)
Pfam (PF01907)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL37
20N60S ribosomal protein L11polymer17820288.51UniProt (P62913)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL5
21O60S ribosomal protein L38polymer708238.91UniProt (P63173)
Pfam (PF01781)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL38
22P60S ribosomal protein L39polymer516426.81UniProt (P62891)
Pfam (PF00832)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL39
23Q60S ribosomal protein L13polymer21124321.71UniProt (P26373)
Pfam (PF01294)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL13
24S60S ribosomal protein L14polymer21523485.01UniProt (P50914)
Pfam (PF01929)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL14
25T60S ribosomal protein L31polymer12514494.91UniProt (P62899)
Pfam (PF01198)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL31
26U60S ribosomal protein L15polymer20424207.31UniProt (P61313)
Pfam (PF00827)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL15
27V60S ribosomal protein L13apolymer20323633.41UniProt (P40429)
Pfam (PF00572)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL13
28W60S ribosomal protein L36apolymer10612477.01UniProt (P83881)
Pfam (PF00935)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL42
29X60S ribosomal protein L37apolymer9210299.41UniProt (P61513)
Pfam (PF01780)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL43
30Y60S ribosomal protein L17polymer18421443.21UniProt (P18621)
Pfam (PF00237)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL22
31Z60S ribosomal protein L18polymer18821687.71UniProt (Q07020)
Pfam (PF17135)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL18
32a60S ribosomal protein L19polymer19623535.31UniProt (P84098)
Pfam (PF01280)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL19
33b60S ribosomal protein L18apolymer17620808.51UniProt (Q02543)
Pfam (PF01775)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL20
34c60S ribosomal protein L21polymer16018610.01UniProt (P46778)
Pfam (PF01157)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL21
35d60S ribosomal protein L22polymer12814813.01UniProt (P35268)
Pfam (PF01776)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL22
36e60S ribosomal protein L23polymer14014892.51UniProt (P62829)
Pfam (PF00238)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL14
37f60S ribosomal protein L24polymer15717825.11UniProt (P83731)
Pfam (PF01246)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL24
38g60S ribosomal protein L23apolymer15617740.21UniProt (P62750)
Pfam (PF03939)
Pfam (PF00276)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL23
39h60S ribosomal protein L26polymer14517303.41UniProt (P61254)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL24
40i60S ribosomal protein L27polymer13615835.81UniProt (P61353)
Pfam (PF00467)
Pfam (PF01777)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL27
41l60S ribosomal protein L28polymer13715784.61UniProt (P46779)
Pfam (PF01778)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL28
42m60S ribosomal protein L8polymer25728088.91UniProt (P62917)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL2
43r60S ribosomal protein L5polymer29734426.81UniProt (P46777)
Pfam (PF17144)
Pfam (PF14204)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL18
44t60S ribosomal protein L32polymer13515898.91UniProt (P62910)
Pfam (PF01655)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL32
45u60S ribosomal protein L35apolymer11012564.71UniProt (P18077)
Pfam (PF01247)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL33
46v60S ribosomal protein L6polymer28832810.21UniProt (Q02878)
Pfam (PF03868)
Pfam (PF01159)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein eL6
47w60S ribosomal protein L7polymer24829291.01UniProt (P18124)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Homo sapiens (Human)Large ribosomal subunit protein uL30
48zProliferation-associated protein 2G4polymer39443851.91UniProt (Q9UQ80)
Pfam (PF00557)
In PDB		Homo sapiens (Human)Cell cycle protein p38-2G4 homolog,hG4-1,ErbB3-binding protein 1
492, 5, 8, F, a...MAGNESIUM IONnon-polymer24.3246Chemie (MG)
50waterwater18.07Chemie (HOH)
Sequence modifications
3: 1 - 503 (UniProt: Q96D46)
PDBExternal DatabaseDetails
Gly 504-expression tag
Ser 505-expression tag
Glu 506-expression tag
Asn 507-expression tag
Leu 508-expression tag
Tyr 509-expression tag
Phe 510-expression tag
Gln 511-expression tag
Gly 512-expression tag
Asp 513-expression tag
Tyr 514-expression tag
Lys 515-expression tag
Asp 516-expression tag
His 517-expression tag
Asp 518-expression tag
Gly 519-expression tag
Asp 520-expression tag
Tyr 521-expression tag
Lys 522-expression tag
Asp 523-expression tag
His 524-expression tag
Asp 525-expression tag
Ile 526-expression tag
Asp 527-expression tag
Tyr 528-expression tag
Lys 529-expression tag
Asp 530-expression tag
Asp 531-expression tag
Asp 532-expression tag
Asp 533-expression tag
Lys 534-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains48
Total formula weight2802914.9
Non-Polymers*Number of molecules246
Total formula weight5979.0
All*Total formula weight2808893.9
*Water molecules are not included.

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PDB entries from 2024-07-10

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