6LPX
Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with 2-oxoglutarate (2-OG)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | D-2-hydroxyglutarate dehydrogenase, mitochondrial | polymer | 481 | 52332.9 | 2 | UniProt (Q8N465) Pfam (PF01565) Pfam (PF02913) In PDB | Homo sapiens (Human) | |
2 | A, B | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | A, B | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 2 | Chemie (AKG) | |||
5 | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A, B: 51 - 521 (UniProt: Q8N465)
PDB | External Database | Details |
---|---|---|
Gly 47 | - | expression tag |
Pro 48 | - | expression tag |
Gly 49 | - | expression tag |
Ser 50 | - | expression tag |
His 522 | - | expression tag |
His 523 | - | expression tag |
His 524 | - | expression tag |
His 525 | - | expression tag |
His 526 | - | expression tag |
His 527 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 104665.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1994.1 | |
All* | Total formula weight | 106659.9 |