6LN6

CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	polymer	1059	116432.5	1	UniProt (P16615) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689) In PDB	Homo sapiens (Human)	SR Ca(2+)-ATPase 2,Calcium pump 2,Calcium-transporting ATPase sarcoplasmic reticulum type,slow twitch skeletal muscle isoform,Endoplasmic reticulum class 1/2 Ca(2+) ATPase
2	A	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)
3	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	A	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)

Sequence modifications

A: 1 - 1031 (UniProt: P16615)

PDB	External Database	Details
Met -27	-	initiating methionine
Gly -26	-	expression tag
Gly -25	-	expression tag
Val -24	-	expression tag
Ala -23	-	expression tag
Met -22	-	expression tag
Pro -21	-	expression tag
Gly -20	-	expression tag
Ala -19	-	expression tag
Glu -18	-	expression tag
Asp -17	-	expression tag
Asp -16	-	expression tag
Val -15	-	expression tag
Val -14	-	expression tag
Arg -13	-	expression tag
Glu -12	-	expression tag
Asn -11	-	expression tag
Leu -10	-	expression tag
Tyr -9	-	expression tag
Phe -8	-	expression tag
Gln -7	-	expression tag
Gly -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Gly -3	-	expression tag
Leu -2	-	expression tag
Ala -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	116432.5
Non-Polymers*	Number of molecules	4
	Total formula weight	609.7
All*	Total formula weight	117042.1

*Water molecules are not included.