6LKA
Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3C proteinase | polymer | 181 | 19976.0 | 1 | UniProt (A9XG43) Pfam (PF00548) | Enterovirus A71 | |
| 2 | B (A) | ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide | non-polymer | 635.7 | 1 | Chemie (EGF) | |||
| 3 | C (A) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A: 1 - 180 (UniProt: A9XG43)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19976.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 635.7 | |
| All* | Total formula weight | 20611.7 |
