6LK4

Crystal structure of GMP reductase from Trypanosoma brucei in complex with guanosine 5'-triphosphate

Replaces:  5X8O

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Guanosine 5'-monophosphate Reductase	polymer	504	53838.2	1	UniProt (Q57ZS7) Pfam (PF00478) Pfam (PF00571) In PDB	Trypanosoma brucei brucei	GMP reductase
2	A	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP)
3	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
4		water	water		18.0	3	Chemie (HOH)

Sequence modifications

A: 1 - 491 (UniProt: Q57ZS7)

PDB	External Database	Details
Lys 492	-	expression tag
Leu 493	-	expression tag
Ala 494	-	expression tag
Ala 495	-	expression tag
Ala 496	-	expression tag
Leu 497	-	expression tag
Glu 498	-	expression tag
His 499	-	expression tag
His 500	-	expression tag
His 501	-	expression tag
His 502	-	expression tag
His 503	-	expression tag
His 504	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53838.2
Non-Polymers*	Number of molecules	2
	Total formula weight	618.2
All*	Total formula weight	54456.4

*Water molecules are not included.