6LHD
Crystal structure of p53/BCL-xL fusion complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | fusion protein of Bcl-2-like protein 1 and Isoform 6 of Cellular tumor antigen p53 | polymer | 375 | 41859.7 | 2 | UniProt (Q07817) UniProt (P04637) Pfam (PF02180) Pfam (PF00452) Pfam (PF00870) In PDB | Homo sapiens (Human) | Bcl2-L-1,Apoptosis regulator Bcl-X,Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 149 (UniProt: Q07817)
A, B: 162 - 358 (UniProt: P04637)
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Pro 1 | - | expression tag |
- | Met 45 | deletion |
- | Glu 46 | deletion |
- | Thr 47 | deletion |
- | Pro 48 | deletion |
- | Ser 49 | deletion |
- | Ala 50 | deletion |
- | Ile 51 | deletion |
- | Asn 52 | deletion |
- | Gly 53 | deletion |
- | Asn 54 | deletion |
- | Pro 55 | deletion |
- | Ser 56 | deletion |
- | Trp 57 | deletion |
- | His 58 | deletion |
- | Leu 59 | deletion |
- | Ala 60 | deletion |
- | Asp 61 | deletion |
- | Ser 62 | deletion |
- | Pro 63 | deletion |
- | Ala 64 | deletion |
- | Val 65 | deletion |
- | Asn 66 | deletion |
- | Gly 67 | deletion |
- | Ala 68 | deletion |
- | Thr 69 | deletion |
- | Gly 70 | deletion |
- | His 71 | deletion |
- | Ser 72 | deletion |
- | Ser 73 | deletion |
- | Ser 74 | deletion |
- | Leu 75 | deletion |
- | Asp 76 | deletion |
- | Ala 77 | deletion |
- | Arg 78 | deletion |
- | Glu 79 | deletion |
- | Val 80 | deletion |
- | Ile 81 | deletion |
- | Pro 82 | deletion |
- | Met 83 | deletion |
- | Ala 84 | deletion |
Gly 149 | - | linker |
Gly 149 | - | linker |
Gly 149 | - | linker |
Gly 149 | - | linker |
Ser 149 | - | linker |
Leu 149 | - | linker |
Val 149 | - | linker |
Pro 149 | - | linker |
Arg 149 | - | linker |
Gly 149 | - | linker |
Ser 149 | - | linker |
Gly 149 | - | linker |
Gly 149 | - | linker |
Gly 149 | - | linker |
Gly 150 | - | linker |
Ser 150 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 83719.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 83850.3 |