6LF3

3D domain-swapped dimer of the maltose-binding protein fused to a fragment of the protein-tyrosine kinase 2-beta

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Maltose/maltodextrin-binding periplasmic protein,Protein-tyrosine kinase 2-beta	polymer	419	46397.6	6	UniProt (P0AEX9) UniProt (Q14289) Pfam (PF01547) In PDB	Escherichia coli (strain K12)	MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,Calcium-dependent tyrosine kinase,CADTK,Calcium-regulated non-receptor proline-rich tyrosine kinase,Cell adhesion kinase beta,CAKB,Focal adhesion kinase 2,FADK 2,Proline-rich tyrosine kinase 2,Related adhesion focal tyrosine kinase,RAFTK
2	G, H, I, J, K...	alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	6	In PDB BIRD (PRD_900001) GlyTouCan (G07411ON)		alpha-maltose

Sequence modifications

A, B, C, D, E, F: 2 - 367 (UniProt: P0AEX9)

PDB	External Database	Details
Met 1	-	initiating methionine
Ala 83	Asp 108	engineered mutation
Ala 84	Lys 109	engineered mutation
Ala 173	Glu 198	engineered mutation
Ala 174	Asn 199	engineered mutation
Ala 240	Lys 265	engineered mutation
Ala 360	Glu 385	engineered mutation
Ala 363	Lys 388	engineered mutation
Ala 364	Asp 389	engineered mutation
Asn 368	-	linker
Ala 369	-	linker

A, B, C, D, E, F: 370 - 419 (UniProt: Q14289)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	278385.5
Branched	Number of molecules	6
	Total formula weight	2053.8
All*	Total formula weight	280439.3

*Water molecules are not included.