6LE8
Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Probable endochitinase | polymer | 380 | 42091.0 | 1 | UniProt (Q11174) Pfam (PF00704) | Caenorhabditis elegans | |
| 2 | B (A) | (4R)-4-(4-ethoxyphenyl)-3-(2-hydroxyphenyl)-5-(pyridin-3-ylmethyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one | non-polymer | 426.5 | 1 | Chemie (EAF) | |||
| 3 | C (A) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 604 | Chemie (HOH) |
Sequence modifications
A: 32 - 411 (UniProt: Q11174)
| PDB | External Database | Details |
|---|---|---|
| Ala 247 | Thr 267 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42091.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 727.8 | |
| All* | Total formula weight | 42818.8 |
