6LDS
Structure of a K245A mutant of L-tyrosine decarboxylase from Methanocaldococcus jannaschii complexed with L-Tyr: External aldimine form
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | L-tyrosine/L-aspartate decarboxylase | polymer | 415 | 47600.7 | 1 | UniProt (Q60358) Pfam (PF00282) In PDB | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | TDC/ADC |
2 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
4 | A | N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-tyrosine | non-polymer | 412.3 | 1 | Chemie (0PR) | |||
5 | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A: 1 - 396 (UniProt: Q60358)
PDB | External Database | Details |
---|---|---|
Met -18 | - | expression tag |
Gly -17 | - | expression tag |
Ser -16 | - | expression tag |
Asp -15 | - | expression tag |
Lys -14 | - | expression tag |
Ile -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Gly 0 | - | expression tag |
Ala 245 | Lys 245 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 47600.7 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 972.8 | |
All* | Total formula weight | 48573.6 |