6L6Y
Crystal Structure of Pluripotency Reprogramming Factor Sox17 mutant (Sox17EK) HMG Domain bound to DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, C) | DNA (5'-D(P*GP*GP*TP*CP*TP*CP*TP*AP*TP*TP*GP*TP*CP*CP*TP*G)-3') | polymer | 16 | 4871.1 | 2 | Homo sapiens | ||
| 2 | B, E (B, E) | DNA (5'-D(*CP*CP*AP*GP*GP*AP*CP*AP*AP*TP*AP*GP*AP*GP*AP*C)-3') | polymer | 16 | 4925.2 | 2 | Homo sapiens | ||
| 3 | C, F (D, F) | Transcription factor SOX-17 | polymer | 83 | 10084.8 | 2 | UniProt (Q61473) Pfam (PF00505) | Mus musculus (Mouse) | |
| 4 | G (D) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | H, I, J, K (A, B, D, F) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
D, F: 66 - 144 (UniProt: Q61473)
| PDB | External Database | Details |
|---|---|---|
| Gly 62 | - | expression tag |
| Ser 63 | - | expression tag |
| Phe 64 | - | expression tag |
| Thr 65 | - | expression tag |
| Lys 122 | Glu 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 39762.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 39858.3 |
