6L6O
Crystal structure of stabilized Rab5a GTPase domain from Leishmania donovani
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rab5a | polymer | 177 | 19382.0 | 1 | UniProt (A0A109NYM0) Pfam (PF00071) | Leishmania donovani | |
| 2 | B (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A: 1 - 175 (UniProt: A0A109NYM0)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asp 58 | Pro 58 | engineered mutation |
| Gly 59 | Pro 59 | engineered mutation |
| - | Pro 60 | deletion |
| - | Arg 61 | deletion |
| - | Gly 62 | deletion |
| - | Ala 63 | deletion |
| - | Ala 64 | deletion |
| - | Ala 65 | deletion |
| - | Ala 66 | deletion |
| - | Pro 67 | deletion |
| - | Gly 68 | deletion |
| - | Gly 69 | deletion |
| - | Ala 70 | deletion |
| - | Thr 71 | deletion |
| - | Ser 72 | deletion |
| - | Ala 73 | deletion |
| - | His 74 | deletion |
| - | Ala 75 | deletion |
| - | Leu 76 | deletion |
| - | Gln 77 | deletion |
| - | Gln 78 | deletion |
| - | Met 79 | deletion |
| Leu 72 | Gln 92 | engineered mutation |
| Ser 87 | Cys 107 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19382.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 618.6 | |
| All* | Total formula weight | 20000.6 |
