6L66
Sirtuin 2 protein with H3K18 myristoylated peptide and intact NAD molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NAD-dependent protein deacetylase sirtuin-2 | polymer | 304 | 34403.7 | 1 | UniProt (Q8IXJ6) Pfam (PF02146) | Homo sapiens (Human) | Regulatory protein SIR2 homolog 2,SIR2-like protein 2 |
| 2 | B (C) | PRO-ARG-LYS-GLN-LEU-ALA | polymer | 6 | 713.9 | 1 | Homo sapiens | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 5 | E (C) | tridecanethial | non-polymer | 214.4 | 1 | Chemie (3LX) | |||
| 6 | F, G (A, C) | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A: 52 - 355 (UniProt: Q8IXJ6)
| PDB | External Database | Details |
|---|---|---|
| Gln 74 | Glu 74 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35117.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 943.2 | |
| All* | Total formula weight | 36060.8 |
