6L15
Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase pim-1 | polymer | 289 | 33292.7 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (Human) | |
| 2 | A | 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazine | non-polymer | 343.9 | 1 | Chemie (E2O) | |||
| 3 | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 29 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Pro 26 | - | expression tag |
| His 27 | - | expression tag |
| Met 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33292.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 343.9 | |
| All* | Total formula weight | 33636.6 |
