6L0S
Crystal Structure of the O-Phosphoserine Sulfhydrylase from Aeropyrum pernix Complexed with L-Cysteine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Protein CysO | polymer | 389 | 41897.6 | 4 | UniProt (Q9YBL2) Pfam (PF00291) In PDB | Aeropyrum pernix K1 | Cystathionine beta-synthase,Cysteine synthase,O-acetylserine sulfhydrylase,O-phosphoserine sulfhydrylase,Serine sulfhydrase |
| 2 | A, B, C, D | (2R)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-propanoic acid | non-polymer | 350.3 | 4 | Chemie (E1O) | |||
| 3 | A, C | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 4 | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 389 (UniProt: Q9YBL2)
| PDB | External Database | Details |
|---|---|---|
| Ala 127 | Lys 127 | engineered mutation |
| Tyr 225 | Phe 225 | engineered mutation |
| Ala 297 | Arg 297 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 167590.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1637.5 | |
| All* | Total formula weight | 169228.0 |
