6L0C
Crystal structure of HIV-1 Integrase catalytic core domain (A128T/K173Q/F185K)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrase | polymer | 170 | 18901.5 | 1 | UniProt (Q76353) Pfam (PF00665) | Human immunodeficiency virus 1 | |
| 2 | B, C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F, G (A) | ARSENIC | non-polymer | 74.9 | 2 | Chemie (ARS) | |||
| 4 | H (A) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
A: 50 - 212 (UniProt: Q76353)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | initiating methionine |
| His 44 | - | expression tag |
| His 45 | - | expression tag |
| His 46 | - | expression tag |
| His 47 | - | expression tag |
| His 48 | - | expression tag |
| His 49 | - | expression tag |
| Thr 128 | Ala 128 | engineered mutation |
| Gln 173 | Lys 173 | engineered mutation |
| Lys 185 | Phe 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18901.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 534.1 | |
| All* | Total formula weight | 19435.6 |
